BOLD PREDICTION: By the end of NS2 life, all Nintendo games will be GKC

[Tober]

Depends if Nintendo wants to utilize the faster Read speeds of the SSD Drive. I believe reading data from the card is about 25% the speed of reading data from the SSD drive.
I believe some devs made comments on this being one of the reasons to use Key cards instead of full physical.

Games that have been designed with no SSD in mind like PS4 ports should be able to run directly from full physical cards. Games that have been designed with the PS5 generation in mind (featuring SSD) will be troublesome to pull of.