I voted RE because it's been so long since Ninty owners got some genuine RE love. That said, a new Metroid Prime game is huge...but it had been announced so long ago that after all this waiting it wasn't really such a big deal in the direct itself, imo.
The only other game that, to me, is super exciting is Hades 2. I'm currently playing it and I've enjoyed it far more than I ever expected to and I am very much looking forward to another. I honestly believe that it is a game no-one should miss out on. It's just that good.







