CRISPR Gene editing used to remove extra chromosome that causes Down Syndrome

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numberwang said:

This can't be applied to humans retroactively?

I'm not an expert myself on this or Down Syndrome, but (remembering back to biology): it would require extensive and careful therapy after the embryonic stage that we have nowhere near the technology to implement. It's probable much of the gene expression that occurs from Down syndrome is already established by the time of birth. In other words, altering the instructions isn't going to change the wiring that's already implemented.