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Two down, three to go. Here's another set of hints.

#45: Super Mario Bros. 3

  • The game that introduced the main villain's children into the series, though in later games this has been retconned and these days they are just the villain's minions.

#44: The Legend of Zelda: Breath of the Wild

  • Some really brittle weapons in this one

#43:

  • The Core and the Arm
  • A four-thousand-year conflict between the two sides

#42:

  • Even more rats
  • She really just can't catch a break

#41

  • A rhythm game built around the music of one of the few video game series that could support an entire game with just its music
  • This was the first home console entry in the spin-off series, having had two handheld titles and an arcade release before this one, as well as another game based on a different series of RPGs