I'm not sure that there are many region locked games these days, but I would think it would be stated in the item description if it were?
As far as just purchasing from LRG, I've done so on 3 different occassions and had no problems. Doom Eternal steel cover edition did take its sweet ass time getting to me, but Shredders Revenge retro edition and Quake 2 arrived as projected.
Best of luck