Currently Online 
I think Nintendo honestly could do $449.99 easily the only reason they might not is because of the trauma of the 3DS and Wii U launch disasters but who knows if Furukawa feels the same way.
But on its own merits, Switch 2 probably could easily be $449.99 and sell out if Nintendo isn't stupid on the software and marketing side.
Even though I'm not big on two SKUs, given the importance of digital downloads today versus 10 years ago that could also be a factor. I could easily see like
Switch 2 - w/64GB or 128GB storage ($399.99)
Switch 2 - w/256GB storage ($449.99)
Launch window lineup, look, performance, and marketing are as big or bigger factors than price. People fixate on the price too much, the GameCube was always cheap, it didn't help, the 3DS was quickly dropped to $169.99 but never could achieve DS level sales and the even cheaper 2DS did not give the system a sales boost, price cuts couldn't stop the Wii from sales decline.
