| haxxiy said: ^ There are some suggestions nirmatrelvir might have a generic immune-suppressing effect since it drops the viral load so dramatically. Hence the possibility of a rebound in cases of a dysfunctional immune response. A longer course of treatment might be the answer but that raises the possibility of viral resistance in the mid to long term. |
Yep, I read up on it some more. It can work so fast your immune system doesn't have time to 'learn' and take over after the 5 day treatment.
I also suspect that that 0.03% comes from mostly healthy people taking the trial. While now it's mostly subscribed to those with weak immune systems and other vulnerabilities. Thus in the 'wild' the number of relapses will naturally be larger. In this case the 'real world' is a biased sample.
Anyway, we got through another night. Oldest is still home in bed as well, lot of coughing, but not doing too bad otherwise. His temperature reads 34.7c, kinda low, but that's normal for him. No fevers, just very tired and coughing.
Glad we still have the usual water is wet articles
https://www.ctvnews.ca/lifestyle/canadians-are-more-sensitive-to-stress-than-before-the-pandemic-report-1.591054
A new report has found that 46 per cent of Canadians are feeling an increased sensitivity to stress than they were prior to the COVID-19 pandemic, impacting their overall mental health. According to the LifeWorks' monthly Mental Health Index released Thursday, many Canadians are expressing more "stress sensitivity concerns" about themselves and their colleagues compared to pre-pandemic levels.
The report found that 49 per cent of working Canadians say they have noticed their colleagues are more sensitive to stress, with 46 per cent indicating the same for themselves. Of those surveyed, 22 per cent said they were unsure. In addition, 45 per cent of employed Canadians said the pandemic has had a negative impact on their ongoing mental health.
Who would have thought! It had a negative impact on down town as well, lot of mom and pop shops are boarded up :(
