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In layman's terms :) Omicron might have picked up a piece of the common cold
https://www.ctvnews.ca/health/coronavirus/omicron-variant-may-have-picked-up-a-piece-of-common-cold-virus-1.5693909

The Omicron variant of the virus that causes COVID-19 likely acquired at least one of its mutations by picking up a snippet of genetic material from another virus - possibly one that causes the common cold - present in the same infected cells, according to researchers.

This genetic sequence does not appear in any earlier versions of the coronavirus, called SARS-CoV-2, but is ubiquitous in many other viruses including those that cause the common cold, and also in the human genome, researchers said.

By inserting this particular snippet into itself, Omicron might be making itself look "more human," which would help it evade attack by the human immune system, said Venky Soundararajan of Cambridge, Mass.-based data analytics firm nference, who led the study posted on Thursday on the website OSF Preprints.

This could mean the virus transmits more easily, while only causing mild or asymptomatic disease. Scientists do not yet know whether Omicron is more infectious than other variants, whether it causes more severe disease or whether it will overtake Delta as the most prevalent variant. It may take several weeks to get answers to these questions.


The theory is, people infected with both Covid and the common cold had the two viruses interacting in their lungs making Omicron possible.

South Africa, where Omicron was first identified, has the world's highest rate of HIV, which weakens the immune system and increases a person's vulnerability to infections with common-cold viruses and other pathogens. In that part of the world, there are many people in whom the recombination that added this ubiquitous set of genes to Omicron might have occurred, Soundararajan said.

"We probably missed many generations of recombinations" that occurred over time and that led to the emergence of Omicron, Soundararajan added.


Looking at the numbers from South Africa https://www.worldometers.info/coronavirus/country/south-africa/
Cases are going up scarily fast, however reported deaths isn't following at all. Good sign.