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haxxiy on 04 October 2021
It seems like cases are in retreat in most places with Eastern Europe being the notable exception.
Still somewhat concerned about vaccine durability... but... these vaccines are still almost a miracle. Intramuscular jabs (except for live attenuated vaccines) almost always fare poorly against respiratory infections. No IgA antibodies so you have to rely on IgG effectively leaking from the blood into the respiratory epithelium.
I assume nasal vaccines are coming but hard to say if they'll arrive in time to be necessary. It might be that three doses last for a long time, and so should the IgA protection from natural infection/breakthroughs.
