haxxiy on 31 August 2021
Data from a Zoe study in the UK show much less waning in vaccine efficacy than Israel, likely a courtesy of the larger gap between doses. Probably won't fall below 50% before 12 - 18 months as opposed to six.
That being said, a six or nine-month booster would likely be even more long-lasting, perhaps dramatically so, given what we know from Polio, Hepatitis, etc. So once again the threat would be variants and not waning.
In a way, that means it's good Delta is so dominant, since it reduces viral entropy (the number of lineages with distinct mutations). You can more safely make a Delta booster because you know the next dominant strain is coming from it.
