| haxxiy said: MERS is often held by medical studies as having an infamously poor antibody response that isn't always readily detectable. To a lesser extent, that was also the case with SARS: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512479/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880093/ The research that the article mentions does refer to detection after 34 months, albeit at reduced levels and taking only select cases (a grand total of seven people) that had detectable antibodies to begin with, to develop a follow-up study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038413/ Why they have decided to present it as some sort of consensus or ordinary feature of MERS? No idea. You are free to draw your own conclusions. Mind you, the same difficulties concerning neutralizing antibody titers and coronaviruses have been noticed all the way back to the 70s: Of course, with MERS and others, the negative results were often credited to issues with the methods used instead of automatically being credited to a proper response being inexplicably absent, since empirical evidence showcases even a mild coronavirus disease protect you for at least about a year of the same virus. One would think that is also the case here, considering how novel the disease and all the tools we have are and how much, time and time again, false negatives have been shown to abound relative to SARS-CoV-2 testing. I understand people want to be careful around this, but some people are acting as if it is the first time a pandemic has happened and nobody knows if the world will end or not. Edit - I haven't found the paper itself, but I've seen a news article where an immunologist mentions a small study on recently infected people found most of them had memory cells but no (detectable) antibodies. So one wouldn't necessarily follow the other or depend on its prevalence too. |
I'm more afraid of the opposite, people not taking it seriously enough and assuming herd immunity will solve the pandemic or it will just go away like sars and mers. The world won't end, but as my wife said (sarcastically), governments just want to let it simmer and kill off some of the elderly to relieve the pension funds. The current focus around the world (except New Zealand and Australia) is to get the economy back up asap, not waiting until the hard to detect asymptomatic cases are stomped out. Just look at the Netherlands now jumping straight to phase 3 while Germany just had a big flare up. Getting people back into planes is more important than protecting those that build our society.
Agreed, better, longer, bigger studies are needed, and more time is needed as well. One thing we have now (unfortunately) is the largest test bed in modern history to study a pandemic. Atm the possibility of re-infection / how well immunity protects you from getting infected (again) is simply unknown. The only 'evidence' atm is that monkeys infected with sars-cov-2 after receiving the Astrazeneca vaccine all got infected anyway. (But received a much larger dose than you would normally get exposed to, and it still prevented pnuemonia at least) https://www.independent.co.uk/news/health/coronavirus-vaccine-oxford-trials-concerns-transmission-astrazeneca-latest-a9521241.html
| JRPGfan said: Just watching a video of john campbell were he says that, one of the "Long term" side effects of getting covid19 is supposedly Diabetes. Also pulmonary fibrosis (lunge scarring). |
No chance it's from eating far less healthy during quarantine?
The causes of diabetes are pretty similar to how a lot of people are spending their time during the isolation :/
- High-fat and carbohydrate diet.
- High alcohol intake.
- Sedentary lifestyle.
- Obesity or being overweight.
Ok, it's not just anecdotal
https://www.sciencedaily.com/releases/2020/06/200612172220.htm
Clinical observations so far show a bi-directional relationship between COVID-19 and diabetes. On the one hand, diabetes is associated with increased risk of COVID-19 severity and mortality. Between 20 and 30% of patients who died with COVID-19 have been reported to have diabetes. On the other hand, new-onset diabetes and atypical metabolic complications of pre-existing diabetes, including life-threatening ones, have been observed in people with COVID-19.
It is still unclear how SARS-Cov-2, the virus that causes COVID-19, impacts diabetes. Previous research has shown that ACE-2, the protein that binds to SARS-Cov-2 allowing the virus to enter human cells, is not only located in the lungs but also in organs and tissues involved in glucose metabolism such as the pancreas, the small intestine, the fat tissue, the liver and the kidney. Researchers hypothesise that by entering these tissues, the virus may cause multiple and complex dysfunctions of glucose metabolism. It has also been known for many years that virus infections can precipitate type 1 diabetes.
Essay Pro