I would say xelda would be the biggest. Here are all of nintendos available franchises.
Animal Crossing
Kid Icarus
Kirby
Donkey Kong
Starfox
F-Zero
Golden Sun
Mother
Pikmin
Pokemon
Zelda
Custom Robo
Star Tropics
Eternal Darkness
Pilot Wings
Mario Spinoff
Wario is coming September
I believe there are many more that I can't remember
Series that may be revived after long dead (games dead since nes/snes/gb)
Kid Icarus
Star Tropics
Now I say nintendo will have alot of new ips, and bring back alot of old series that have been gone a generation or two or three.