Bill Trinnen claims Bayo 3 is coming "sooner than expected, later this year" so at least that means there's a good chance she'll be at E3.
Only thing is I kinda doubt it'll be coming this year if only cos Astral Chain is hitting in August and releasing 2 action games from Platinum just a few months apart seems like overcrowding. I suspect Nintendo will slip Bayo 3 into early 2020 like with Tropical Freeze and Yoshi's Crafted World.