If it's a real Nintendo direct, and not just a mini one:
- Yoshi's CW release date
- Fire Emblem: TH release date
- a Wii U port (I'll bet on a Zelda one)
- a bunch of indie games
- a new Mario game (there's several Mario games each year, so far only NSMBU has been announced)
- no Animal Crossing, Pokémon, Metroid Prime 4 or Luigi's Mansion news