Captain Marvel could do great.
They're going to play on the IW2 introduction with the past of Thanos, and you can expect lots of "First Marvel female superhero" articles...
Agreed. If America goes as crazy for Captain Marvel as they did for Black Panther just because of the fact she's a female superhero, then it will easily gross over a billion worldwide.
Whether the hype of IW results in better sales will be tested next month with Ant Man. If it manages 800+ million than Captain Marvel is almost guaranteed a Billion.