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While I think Pokemon Switch will sell extremely well (Like 25 million) I think beating Red/Blue is a huge stretch. Due to the amount of sequels per console Pokemon games are more front loaded, it'll still do great numbers, but I think beating Gen 1 is highly unlikely.

Animal Crossing is possible, but not a guarantee. If it's kinda lazy like City Folk I wouldn't put much stock in it, but if it's great, then I think there's a good chance.

Metroid Prime 4 is the most likely of all of these. Unless it sucks it's hard to see how it won't pass 3 million.