Round 1A - is the most obvious, imo - MH does NOT have splatoon legs, and it's going to be very close after the first few weeks of sales - so, in the long run, easily Splatoon.
Round 1B - MH. Especially if we count digital, otherwise, it's close.
Round 2A - Splatoon, I think, by a small margin. Again, I don't think MH has comparable legs, and it's currently close.
Round 2B - I don't know, about equal.
Round 3 - I'd go with MH
R4 - If digital/PC is included, MH wins, I think, should still be close. Only taking physical, or only taking console sales, I'd say Zelda.
Bet with PeH:
I win if Arms sells over 700 000 units worldwide by the end of 2017.
Bet with WagnerPaiva:
I win if Emmanuel Macron wins the french presidential election May 7th 2017.