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Liquids system control is through the use of nano machines which snake has inside him, they tell you that in the cutscene with Naomi i believe in like act 2. The new foxdie and the story behind that is explained later on in the game, actually its explained in a movie in the middle of the credits so make sure when you beat the game you pay attention. Snake isn't dieing because of the foxdie, he's dying because thats how he was made, he's a clone with shortened telomeres making him age quicker, the fox die is a virus inside him that is becoming mutant so, it wont affect him necissarily, it will kill those around him however once it becomes airborne.

 

Hope this helps. Make sure you watch every cutscene, you never know what you might miss.