The Sims. Previous iterations have done relatively well on Nintendo systems (even the fairly obscure Sims 3 with very little marketing release on 3DS did well at about 700k sold).
While I would say the Sims is the perfect litmus test, Sim City and Plants VS. Zombies (the original and potentially the second one; not the FPS Garden Warfare games) would also most likely do well on the eShop.