Wright on 15 March 2017
Honestly, the best advise I could give you to play Fallout without having any clue is mark a spot in your map that's far away and just try to reach that place. Stop by any place you met through the way, and always loot everything you can from your enemies, but always try reaching that specific point in mind. Everything else will start coming to you.
Once you reach that point, just aim for a new point. Rinse and repeat. You'll eventually have things figured out, and this way you don't really have to worry about much, but just the travel itself.
