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We already have 64, 128 and even (I think) 256 GB MicroSDs. Why wouldn't the cartridges be able to store more than 50Gb? Also, they will probable use different cartridge sizes for different games; Nintendo is usually very effective in keeping their games to a minimu size, so expect 8, 16 and 32 GB game cartridges for Nintendo and other 3rd Company "smaller" games and 64 and 128 GB cartridges for more graphically "intense" games, and for GoTY, Legendary and Complete editions.