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superchunk said:

I for one am very excited to see this. I loved Nexus phones due to remaining pure Android, no bloatware and carrier unlocked.

Great camera, casing, CPU/GPU, storage, upgrades to Google services, vanilla Android and universally unlocked...

AFAIK, it is NOT universally unlocked, only those bought direct from Google,
they are also selling them thru carriers such as Verizon and ones found in retail stores may likely be Verizon versions.
In these cases, Verizon can "customize" the OS, and is in control of OS updates
 (although they will likely benefit since exact hardware spec is being targetted for updates by Google).

So really, the question is what is specially attractive here vs. Nexus phones or similar near-vanilla phones (e.g. Motorolla as mentioned)
Specific hardware differences per model, but drawing from all manfacturers (Moto, Xiaomi, etc) should close to match any spec.

superchunk said:

Due to the weak point of a SD card connector and the type of SD Card you use, the data transfer ... is noticeable[y weak]. 

Most SD cards are weak.  If performance is important to you, get a high-spec card.  Not really inherent to removable/SD card concept. 
People mentioned Samsung's UFS, and in fact they are introducing removable cards using that spec, with speeds equivalent to SSD.
Certainly, one also needs a high-spec reader to use those fully, but that does not mean that built-in is the only option for performance.