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For me personally, no, I've always been pretty much the typical guy and identified pretty much solely with male things.

That said we are all female early in the embryo phase, it's only with hormones that some fetuses become male, if I'm remembering my high school bio class correctly.

So I dunno. For others maybe there can be a "malfunction" as it were that makes some people strongly identify with the opposite gender.

If people who feel they are the wrong gender were truly mentally ill they should have problems processing other parts of reality, as virtually all mentally ill people do (ie: they generally don't just believe one delusional thing, it's usually like 20-30+ with new strange thoughts evolving all the time) but that doesn't seem to be the case with transgender people, so I don't believe it's a mental disease or anything like that.

If we say "well nature intended it to be that, so too bad" ... have you studied nature? Nature is a gender bending sex freak, where some species can change their sex in the wild even, others have sex where the female ends up eating the head of the male, and homosexuality in the animal kingdom is commonplace.

I don't know if it's impossible to think that some of these concepts might be more fluid than our uptight society might admit to.