Aonuma: We are making something new with Zelda HD as OoT was

[Miyamotoo]

At this point its obvious they will show Zelda U with name, full trailer and release date (Q4) at E3, most likely running on NX (to marketing NX, but of course game will be released for Wii U). Smaller chances are that we will maybe see Zelda U on NX reveal before E3.