PS4 + PC (with some 3DS/Vita sprinkled in) works best for me. With PC i can play the majority of multi-platform titles with the frame-rate, IQ, and graphics settings i want, and have access to a very wide variety of exclusives (many in genres that don't usually make their way to consoles). With the PS4 i have access to more console exclusives i'm interested in than on the WiiU and X1, and can be confident that i'll be able to play the majority of major 3rd party home console titles from Japan.
The WiiU would probably be my 2nd home console pick, but relative to the other two it gets very few games i want. I wouldn't be willing to give either up for it. Fortunately i usually end up with all the platforms by the end of a generation regardless, so it's less a matter of 'i wouldn't give up [x] for [y]', and more 'i'd rather have [x] now, and [y] later'. Later in this instance being whenever the hell Zelda U comes out :p
