No, it won't be the last Wii U focused Nintendo Direct, but maybe thr last 3DS focused Direct, because the 3DS will be replaced first, namely in 2016. We will get another ton of Wii U Directs in 2016.
My predictions for the Direct:
-Twilight Princes HD with Q1 2016 release
-Pikmin 4 with Summer 2016 release
-new Download Game for Wii U that will launch after the presentation
-Sega Master System Virtual Console on Wii U
-New Star Fox Zero trailer + Releasedate
-DLC announcements for Tri Force Heroes, Super Mario Maker and Ultra Smash
-More Smash DLC
-New Hyrule Warriors Legends Trailer + Details on Wii U content
-New Pokken Character
-new amiibo
-short mention of Nintendo Account, My Nintendo, Miitomo
-Zelda Wii U Ganeplay with Eiji Aonuma in the end







