Mario and DK are already a thing. 
I'm hoping we get a Metroid near the end of the Wii U's life, or near launch for NX.
As for F-Zero, I'm not expect that series anytime soon...
"Just for comparison Uncharted 4 was 20x bigger than Splatoon 2. This shows the huge difference between Sony's first-party games and Nintendo's first-party games."







