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Wait, do you mean design like the "looks?" Or design like how comfortable it is? Design/looks-wise, Vita hands-down for me. It is absolutely gorgeous to behold.

Comfort-wise, I'd have to go with GBA SP. I adore my Vita, but when I play it, my hands start cramping since I find the thumbsticks to be too low. Same with the 3ds XL and any game that requires the d-pad on it. Cramp city (Population: me). I could play my GBA SP for hours and never feel anything. It felt like an extension of my hands.



It'll be awhile before I figure out how to do one of these. :P