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Toxy said:
curl-6 said:

Well, as its larvae live in freshwater outside the human body, it would factor into the ecology somewhat. The larva, for example, infect copepods prior to human consumption.

It essentially kills copepods and infects people. There are other animals within the ecosytem that eat copepods, so by removing the guinea worm, this would not create consequence within the ecosystem; nothing eats the guinea worm for survival. It is simply a being that does not offer any virtues; all it offers is death.
Killing it is certainly ethical, especially considering how some countries are plagued with them. 
Want some water to survive? Nope - this sucker will teach you a lesson for trying to survive.

To play Devil's Advocate, as small aquatic organisms, they are presumably preyed upon by things like fish or aquatic insect larvae.