I very much doubt this game will be anywhere near 50GB. We have to be talking about 25GB as the limit. If I remember right, the textures don't look all that detailed and it's not like they'll need to ship high-def textures for PCs set to ultra on the disc. Visual assets are probably not all that large.
The main culprits for large file size are almost always pre-rendered video and audio files.
Regardless, Nintendo really needs to do a better job at memory management next gen. The 8GB model was such a huge mistake and it hurt the entire console down the line.








