I think 2016 is really soon for the next handheld. I guess it will come out 2017, with the home console counterpart. About the launch titles, I think the best ones would be the 7th Gen of Pokémon (because that sells a lot), a Mario game (at this point all of them are just fillers, but everybody like them anyway) and a Metroid game.
This way they can reach to the main niche gamers (the RPG lovers, the casual ones and the "hardcore" gamers). Of course, 3rd party and maybe a remake would be present too.







