If you take a simple search on VGChartz database (no PC) and take away all Nintendo related titles (in the USA and Europe it is Wii Sports and Mario Bros, in Japan it is Pokémon, Animal Crossing and Mario Bros ) then you will get these top lists:
Japan
Monster Hunter
Dragon Quest
Final Fantasy
Youkai Watch
Street Fighter
Gran Turismo
Hot Shots Golf
A long way down the list there are the JRPGs: Yu-Gi-Oh, Chrono Trigger, Mana, Kingdom Hearts, Romancing SaGa, Dragon Ball, Inazuma Eleven. At place 171 on the RPG top list there is the first Persona game.
Europe
GTA
CoD
Gran Turismo
FIFA
Kinect Adventures!
Mario & Sonic at the Olympic Games
Just Dance
Europe is often described as the region for racing games: except for Gran Turismo the first racing game on the top list is Need for Speed Underground 2 on place 58.
North America
Kinect Adventures!
GTA
CoD
Halo
Just Dance
The Elder Scrolls
Sonic the Hedgehog
Battlefield
Madden
Gears of War
Gran Turismo
