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Lot of people also voting for Metroid.

The fun thing about Metroid is it could be done in a variety of ways, preferably just not like Other M.

Naturally, it was influenced by Aliens and Metroid could be approached more like a action based horror film, or it could take its cues from the original Alien and be a lot more like a sci-fi survival psychological horror genre film that played off the limited/recovered resources in darkened, confined and deserted spaces theme.

They could cover the themes of off world colonialism, interstellar travel, human gene/cybernetic modification/enhancement, etc. A lot of fun could be had exploring the options based upon themes addressed in the Metroid franchise.