Grim Fandango on Vita. It will be just as awesome as Full Throttle on PSP, if only Fandango wasn't such a hassle to play as it is a classic 'classic adventure' - getting stuck all the time, countless hours of backtracking, trying every inventory item on everything. I think Fandango is my favorite terrible game.
Deus Ex (2000) - a game that pushes the boundaries of what the video game medium is capable of to a degree unmatched to this very day.