I dont know if it counts as a "cutscene," per se, but the scene in Planescape: Torment where The Nameless One interacts with a sensory stone and sees one of his past incarnations speaking with Deionarra always does it for me. That writing helps the scene come across better than any CGI cutscene ever could.
For literal cutscenes, though, the scene in Beyond Good and Evil after the children are abducted from the lighthouse always strikes me as particularly tear-jerking. Whoever did Jade's voice actor is incredibly talented.
And for pure awesome value, in the final Legacy of Kain game, finally seeing Moebius, the character who had been manipulating things from the shadows for the entire series, impaled first by Kain, and then by Raziel on the spiritual plane, nearly made me Dean-scream.
"'Casual games' are something the 'Game Industry' invented to explain away the Wii success instead of actually listening or looking at what Nintendo did. There is no 'casual strategy' from Nintendo. 'Accessible strategy', yes, but ‘casual gamers’ is just the 'Game Industry''s polite way of saying what they feel: 'retarded gamers'."