36. Shadow of the Colossus (PS2, remade in HD as part of ICO/SotC package on PS3)
This is typically held up as a prime example when people start describing games as an art form and it's pretty easy to see why. Unlike a lot of arty style media, this also had the bonus of being an entertaining game. The simple concept of a game filled with epic boss fights in a wonderfully unique environment just plain works, but the real beauty of the game comes in the subtle ways the game invokes emotional responses from the player, from the expressions on the colossi to the way Agro responds as if riding a real horse.