No one got my no. 50. The "flesh eating" was a reference to the zombies. The "dog" was in reference to the developers Naughty Dog!
50. The Last of Us (PS3)
The first new entry in my list. Naughty Dog did an amazing job in weaving a powerful, emotionally draining narrative with clever AI, immersive environments and solid third-person mechanics. The result is a storytelling masterpiece for the industry and proof that even big budget developers don't have to play it safe with new IPs.