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RolStoppable said:
It has to do with the fact that the main target demographic for today's blockbuster games are male teenagers, so games have to be designed in a way that allows the player to live out adolescent male fantasies. This usually means a tough guy who kills stuff and impresses the ladies (if there are female characters in the games). Assuming the role of a female lead character is a very unmanly thing to do.

This.

Also, the kind of games that are more popular with women tend to have either optional genders for the player character, or characters where gender is rather immaterial.