Metroid has never been a system seller.
HOWEVER,
If they made a great solo-experience (building from Super Metroid) as required for said series and then add a FPS style multiplayer with big maps, holes to roll through, various limited upgrades, 24v24 (as min) sized battles and all the many player options that are seen in other shooters... it could be a new hit.
Playable characters as various samus types, other bounty hunters with similar skills, space pirates with special flying capabilities to offset no ball usage, etc... I think it would be awesome.







