For now it's definitely between The Last of Us and Bioshock Infinite. Fire Emblem: Awakening has the problem of being niche and on a handheld system. The last handheld game to be nominated for a decent amount of GOTY awards was Super Mario 3D Land, which is the exact opposite of niche, so aside from a few nominations here and there, I don't think it'll make a splash. However, it's an obvious frontrunner for the Handheld Game of the Year award, if not Best 3DS Game Yet.
Those are the only three major releases with 90+ metascore, though there are many good games in the 85-89 range. Future possible contenders include Batman: Arkham Origins, GTAV, Watch_Dogs, A Link to the Past 2, and Infamous: Second Son, to name a few.
3DS Friend Code: 0645 - 5827 - 5788
WayForward Kickstarter is best kickstarter: http://www.kickstarter.com/projects/1236620800/shantae-half-genie-hero
