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1. Assuming you're at home, as soon as shit hits the fan fill up tub and all bottles with water (before water goes off), prepare bug out bag and create/gather some weapons (all melee for me, as in UK). Barricade your home, if you live in a house with multiple floors or an attic, go upstairs and either destroy the staircase or block it with furniture. I live in a flat on the 2nd floor so all I need to do is barricade my front door.
2. wait out initial panic in your home for a few days.
3. venture out in search for food, water, better weaponry, books on all sorts of aspects on survival (first aid, growing food etc.) but avoid all big stores, stick to homes and convenience shops, and stay local.