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A partnership with Konami to get some soccer games and maybe later a Castlevania or Metal Gear release.

A partnership with Capcom, keeping the next few main Monster Hunter games exclusive to Nintendo systems and maybe cooperative project reviving Mega Man or something.

A partnership with a major western developer to release a brand new IP or another major title similar to Metriod or something like that might also do wonders for Nintendo's rep provided the results are stellar.