Disease wasn't the only factor that destroyed the Native Americans.
If the Native Americans could have gotten past their grudges against each other and united as one during the 1812 war they could have stopped the Americans from advancing west, and the U.S. could very well have ended at the appalachian mountains.
Before the Revolutionary war, Britain thought they never had to worry about the American people revolting, because they believed that they could never unite as one and thus were not a threat. They also made measures throughout their rule to keep tensions high between colonies and forbid united meetings and such. They did though bring all the colonies together to fight the French/Indian war. That was the first time that all the colonies worked together, and it was ironically by Englands behest. Later America would unite over the whole taxes situation and finally revolting against England.
But it was all about them all coming together. The Indians never were able to, despite the efforts of Tecumseh to unite all his people against the Whites. More often than not in the Indians history the white people used native american grudges against each other. Say you have 3 Indian tribes, "A", "B", and "C". They all hated each other. the white people would attack "A". The Indians "B" or "C" would help the white people destroy "A" because they were hated long time rivals. Then later the Whites would attack "B", the very same tribe that just got done helping htem years earlier. Ironically enough "C" would then jump in and help destroy "B" because again long time hatred between them. This happened many a times, and ulimately was the demise of the Indian Power in america.
The age old saying "the enemy of my enemy is my friend" is not the best philosophy. The Native American's history is proof of that.







