I've discovered a few issues not mentioned. Setting your audio settings to surround has the potential to screw up audio in some games. Specifically Darksiders II. If your WiiU is set to surround, Darksiders 2 ignores the center channel for sound effects and voice audio. This wouldn't be troublesome, except that the center channel is the only channel Voice audio comes from. Changing the Wii to stereo fixes the problem.
Similarly, surround sound isn't true dolby digitial surround sound. Its Pro Logic II surround, which is Surround sound buried in a stereo stream. Even less excuse for the surround sound issues mentioned above.
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