If Zombi U is a good game it will do well. So will BLOPS2.
Sonic Racing, Epic Mickey 2, will as well. FIFA, Scribblenauts, and Assassin's Creed 3 will do OK.
Mass Effect 3, Tekken Tag, Ninja Gaiden 3, Batman: Arkham City (too expensive), etc. will not do so great. I think top sellers will basically go ...
1. New Super Mario Bros. U
2. Call of Duty: Black Ops 2
3. Zombi U
4. Nintendo Land (many will get it bundled rather than seperately)
5. Sonic All-Stars Racing 2
6. Epic Mickey 2
7. Assassin's Creed 3
8. Scribblenauts
Will be the top sellers.