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They can de-age (baby mario and luigi) but Nintendo would never allow a Mario or Luigi son or daughter.
With good reason. It would lost the magic. Good videogame characters don't need evolution. Evolution always lead to an end - or the famous "back to basics" or reboot. Mario never needed any of the sort, thankfully. Long live saving the princess.

But in Partners in Time they did more or less what you want. Adult Mario and Luigi fought alongside their "sons", themselves as babies. Not the same, but it felt like it, them protecting the babies like parents.