So, things like Pokemon (which are RPG's but have little actual discussion) might be able to get a Global Release? Pokemon is a very large franchise so I would think that would be a good idea for it.
Sadly, I don't think so. All the names have to be translated, as do the descriptions for each 'mon, and the guides, and the descriptions, and all the other trainers...
It's not so big an issue as many, though.
I think it should be possible to do Japan then Europe/America, though. Or the other way round. If everything is translated for the EU countries, then America should follow suit quite swiftly after.