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mrstickball said:
When you replay, it saves your statistics for EVERYTHING for achievements.

Therefore, it keeps your statistics on:

Missions with squad mates
Side Quests with squad mates
Uses of various biotic/tech powers
# of kills with various weaponry.

Therefore, unlocking those achievements is much easier 2nd time around with your first game's character.

Sweet. I am having a blast having the pulse rifle and maxed out charisma and intimidation. I love it!