Dragon Age 2:
Whilst Dragon Age Origins had some amazing old school gameplay combined with an epic story and journey, Dragon Age 2 had basic combat with little to no tactics (endless waves of enemies didn't help), poor character creation and a stream of reused art assets and levels. The whole game was uninspiring and even a good (albeit a personal) story and interesting cast of characters didn't really help matters.
Final Fantasy XIII
I won't go into details as it's already been covered in many threads. Basically, overly linear, poor cast, poorly told story, over reliance on datalog, lack of variety etc.
Deus Ex: Invisible War
Deus Ex was the greatest game of all time (as voted for by PC Gamer UK). The sequel did everything to simplify the game down for console players to the point most console players think "wtf is this?!". Still had an involving story and felt Deus Ex-like in places but small levels, overly simplified RPG elements, and some rather odd questlines (e.g. "You're responsible for the death of my wife.... but I will give you a chance to redeem yourself with this new quest!") left it an average experience.
Call of Duty 3:
Didn't realise it was a different developer. One of the worst FPS' I've ever played. Can see why they didn't bother with a PC version.