This is hard considering that it is IMO the best platform ever made:
Overall Best Game: Mario Kart DS
Best 1st Party Game - Mario Kart DS
Best 3rd Party Game - The World Ends With You
Best DSiWare Game - Art Style Picopict (I think its Picto bits in US)
Best Game Design - The World Ends With You
Best Unique Game - Scribblenauts
Best Launch Game - Super Mario 64 DS
Best Visuals Graphically - Dragon Quest IX
Best Visuals Artistically - The World Ends With You
Best Soundtrack - The World Ends With You
Best Port - Chrono Trigger
Best Remake - Pokemon Heart Gold/Soul Silver
Best RPG - Pokemon Black/White
Best Platformer - New Super Mario Bros
Best Puzzle - Art Style Picopict
Best Shooter - Metroid Prime: Hunters
Best Adventure - Zelda: Spirit Tracks
Best Strategy - Advance Wars: Dark Conflict (DoR in US)
Best Racing - Mario Kart DS
